Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50018264
TargetNuclear receptor subfamily 4 group A member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50378798(CYTOSPORONE B)
Affinity DataEC50:  0.115nMAssay Description:Inhibition of Gal4-fused Nur77-LBD in human BGC-823 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409208(CHEMBL5289973)
Affinity DataEC50:  3nMAssay Description:Inhibition of RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50218464(4-(5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-tetrah...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409209(CHEMBL5273291)
Affinity DataEC50:  16nMAssay Description:Antagonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409210(CHEMBL5278384)
Affinity DataEC50:  240nMAssay Description:Antagonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409212(CHEMBL5277896)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50178961(CHEMBL2385268)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50553255(CHEBI:17898 | All-Trans-Retinal | Retinal)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50378798(CYTOSPORONE B)
Affinity DataEC50:  0.278nMAssay Description:Inhibition of Gal4-fused full length Nur77 in human BGC-823 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409207(CHEMBL5279494)
Affinity DataEC50:  376nMAssay Description:Inhibition of RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataKd:  290nMAssay Description:Binding affinity to Nur77 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409489(PROSTAGLANDIN A2 | CHEBI:27820)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to Nur77 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Mouse)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409498(CHEMBL5268689)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of Gal4-fused Nurr1 in mouse MN9D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Rat)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409498(CHEMBL5268689)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of full-length Nurr1 in rat N27-A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM22971(Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of Gal4-fused Nur77 in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM22971(Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...)
Affinity DataEC50:  900nMAssay Description:Inhibition of full-length Nurr1-RXRalpha in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409501(CHEMBL5278637)
Affinity DataEC50: <1nMAssay Description:Inhibition of human full length Nurr1-RXRalpha transfected in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409206(CHEMBL114640)
Affinity DataEC50:  8nMAssay Description:Inhibition of RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409208(CHEMBL5289973)
Affinity DataEC50:  23nMAssay Description:Inhibition of RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409207(CHEMBL5279494)
Affinity DataEC50:  36nMAssay Description:Inhibition of RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409206(CHEMBL114640)
Affinity DataEC50:  24nMAssay Description:Inhibition of RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409208(CHEMBL5289973)
Affinity DataEC50:  0.580nMAssay Description:Inhibition of RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409207(CHEMBL5279494)
Affinity DataEC50:  32nMAssay Description:Inhibition of RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409206(CHEMBL114640)
Affinity DataEC50:  3nMAssay Description:Inhibition of RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Agonist activity at RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409205(CHEMBL5280414)
Affinity DataEC50:  232nMAssay Description:Agonist activity at RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409205(CHEMBL5280414)
Affinity DataEC50:  98nMAssay Description:Agonist activity at RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50409205(CHEMBL5280414)
Affinity DataEC50:  29nMAssay Description:Agonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed