Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50014210
TargetCollagenase 3(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant human MMP13 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM16596(N,N -bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-di...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP13 (unknown origin) using APMA as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM50573596(CHEMBL4846182)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM50573597(CHEMBL4860977)
Affinity DataIC50: 100nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetStromelysin-2(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human MMP10 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human MMP9 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of recombinant human MMP8 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP12 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMatrilysin(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP7 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP3 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP1 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Bolderbiopath

Curated by ChEMBL
LigandPNGBDBM256500(BDBM256501 | US9505743, 44)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP14 using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as substrate measured every 5 mins for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed