Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50014297
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574637(CHEMBL4862351)
Affinity DataIC50: 0.245nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574628(CHEMBL4869024)
Affinity DataIC50: 0.763nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574633(CHEMBL4870265)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574627(CHEMBL4875985)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574629(CHEMBL4870560)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574638(CHEMBL4862976)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574626(CHEMBL4858714)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574625(CHEMBL4861707)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574628(CHEMBL4869024)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574630(CHEMBL4858409)
Affinity DataIC50: 16nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574637(CHEMBL4862351)
Affinity DataIC50: 32nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574634(CHEMBL4858535)
Affinity DataIC50: 45nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574634(CHEMBL4858535)
Affinity DataIC50: 47nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574627(CHEMBL4875985)
Affinity DataIC50: 48nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574632(CHEMBL4871985)
Affinity DataIC50: 50nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574635(CHEMBL4851795)
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574630(CHEMBL4858409)
Affinity DataIC50: 57nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574635(CHEMBL4851795)
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574629(CHEMBL4870560)
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574625(CHEMBL4861707)
Affinity DataIC50: 69nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574636(CHEMBL4873830)
Affinity DataIC50: 81nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574626(CHEMBL4858714)
Affinity DataIC50: 99nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574631(CHEMBL4849337)
Affinity DataIC50: 114nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574624(CHEMBL4848234)
Affinity DataIC50: 117nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574633(CHEMBL4870265)
Affinity DataIC50: 118nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574632(CHEMBL4871985)
Affinity DataIC50: 119nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574631(CHEMBL4849337)
Affinity DataIC50: 126nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574624(CHEMBL4848234)
Affinity DataIC50: 169nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50574636(CHEMBL4873830)
Affinity DataIC50: 199nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 568nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured after 60 mins by ADP-Glo kinase based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed