Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50014929
TargetGamma-aminobutyric acid receptor subunit beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GABAB1b receptor expressed in RBL cells by microplate analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581244(CHEMBL5086734)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581243(CHEMBL5089881)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581249(CHEMBL5073182)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 186nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50032829(CHEMBL1836968)
Affinity DataIC50: 510nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581245(CHEMBL5091401)
Affinity DataIC50: 882nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581247(CHEMBL5090616)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human GABAB1b receptor expressed in RBL cells preincubated for 5 mins followed by 3-APMPA addition by microplate analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed