Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50014925
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581173(CHEMBL5071427)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581167(CHEMBL5077068)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581172(CHEMBL5082628)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581178(CHEMBL5080333)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50521388(CHEMBL4544864)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581176(CHEMBL5083140)
Affinity DataIC50: 22nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581175(CHEMBL5076716)
Affinity DataIC50: 24nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581164(CHEMBL5083709)
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581168(CHEMBL5094231)
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581174(CHEMBL5092549)
Affinity DataIC50: 38nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581165(CHEMBL5073242)
Affinity DataIC50: 41nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581160(CHEMBL5079421)
Affinity DataIC50: 49nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581170(CHEMBL5079692)
Affinity DataIC50: 53nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581169(CHEMBL5094290)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581166(CHEMBL5084713)
Affinity DataIC50: 128nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581163(CHEMBL5079367)
Affinity DataIC50: 148nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581162(CHEMBL5078451)
Affinity DataIC50: 153nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 910nMAssay Description:Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 960nMAssay Description:Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of PDE7A1 (130 to 482 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of PDE10A (449 to 770 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581161(CHEMBL5083028)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10A (449 to 770 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE11A4 (588 to 911 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE11A4 (588 to 911 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2A (580 to 919 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A1 (130 to 482 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D2 (86 to 413 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D2 (86 to 413 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (679 to 1087 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581171(CHEMBL5077120)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (679 to 1087 residues) (unknown origin) using [3H]-cAMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2A (580 to 919 residues) (unknown origin) using [3H]-cGMP substrate measured for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50581177(CHEMBL5075032)
Affinity DataKi:  7nMAssay Description:Binding affinity to PDE9A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed