Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50014107
Affinity DataEC50: 760nMAssay Description:Inverse agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as inhibition of Th17 cells differentiation by measuring decrease in I...More data for this Ligand-Target Pair
Affinity DataEC50: 546nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 148nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 358nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+3nMAssay Description:Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...More data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...More data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at ROR-gammat (unknown origin) by dual FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at ROR-gammat (unknown origin) by dual FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 58nMAssay Description:Agonist activity at N-terminal GST-fused human RORgammat (259 to 518 residues) expressed in Escherichia coli BL21(DE3) by FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.98E+3nMAssay Description:Inverse agonist activity at europium-labeled human RORgammat LBD assessed as inhibition of XL665-labeled co-activator SRC1 recruitment incubated for ...More data for this Ligand-Target Pair
Affinity DataEC50: 570nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 740nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.24E+3nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 1.23E+4nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 560nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 2.23E+3nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 670nMAssay Description:Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+3nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 97nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 355nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 982nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 138nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 221nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataEC50: 215nMAssay Description:Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inverse agonist activity at europium-labeled human RORgammat LBD assessed as inhibition of XL665-labeled co-activator SRC1 recruitment incubated for ...More data for this Ligand-Target Pair
