Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50011497
TargetNeurotensin receptor type 1(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548041(CHEMBL4794546)
Affinity DataEC50:  20nMAssay Description:Agonist activity at rat NTR1 expressed in CHO cells assessed as effect on [3H] phosphoinositide accumulation using neurotensin (1 to 13 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548042(CHEMBL4797453)
Affinity DataEC50:  500nMAssay Description:Activation of human MrgprX1 expressed in BAM 8-22 activated-rat KNRK cells by fura2-AM dye based calcium imaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548043(CHEMBL4754112)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of human MrgprX1 expressed in BAM 8-22 activated-rat KNRK cells by fura2-AM dye based calcium imaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548044(CHEMBL4787743)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of human MrgprX1 expressed in BAM 8-22 activated-rat KNRK cells by fura2-AM dye based calcium imaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548045(CHEMBL4757433)
Affinity DataEC50:  3.00E+3nMAssay Description:Modulation of rat ASIC3 expressed in Xenopus laevis oocytes at -70 mV holding potential by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548046(CHEMBL4763929)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human V1bR expressed in African green monkey COS-1 cells assessed as increase in intracellular calcium response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548047(CHEMBL4753825)
Affinity DataEC50:  12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548048(CHEMBL4764550)
Affinity DataEC50:  12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548049(CHEMBL4751178)
Affinity DataEC50:  12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548050(CHEMBL4762540)
Affinity DataEC50:  12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50548051(CHEMBL4748140)
Affinity DataEC50:  12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed