Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50012463
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50084631(CHEMBL3427203)
Affinity DataIC50: 5nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 8nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50096276(CHEMBL1235806)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50: 41nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557782(CHEMBL4800072)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557783(CHEMBL4784073)
Affinity DataIC50: 90nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557782(CHEMBL4800072)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557783(CHEMBL4784073)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557784(CHEMBL4797035)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 350nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557784(CHEMBL4797035)
Affinity DataIC50: 400nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 440nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50: 480nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 900nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557781(CHEMBL4788232)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557780(CHEMBL4755592)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557778(CHEMBL4745938)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557781(CHEMBL4788232)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50084631(CHEMBL3427203)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557779(CHEMBL4761793)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557778(CHEMBL4745938)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557780(CHEMBL4755592)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557777(CHEMBL4757602)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557777(CHEMBL4757602)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50096276(CHEMBL1235806)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557779(CHEMBL4761793)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50033277(CHEMBL3357103)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557780(CHEMBL4755592)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 8.09E+4nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557784(CHEMBL4797035)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557783(CHEMBL4784073)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557782(CHEMBL4800072)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557781(CHEMBL4788232)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557779(CHEMBL4761793)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557778(CHEMBL4745938)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557777(CHEMBL4757602)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed