Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50013217
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human C-terminal His-tagged PD-L1 (18 to 239 residues)/human C-terminal IgG epitope-tagged PD1 (25 to 167 residues) expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM440668(US10639284, Compound 2.019 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human PD1/PD-L1 preincubated with PD-L1 for 1 hr followed by incubation with PD1 for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563739(CHEMBL4779400)
Affinity DataIC50: 1.83E+3nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin) assessed as disruption of PD-1/PD-L1 complex by measuring PD-L1 dimerization measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563737(CHEMBL4740244)
Affinity DataIC50: 9.33E+3nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin) assessed as disruption of PD-1/PD-L1 complex by measuring PD-L1 dimerization measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563736(CHEMBL4748878)
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin) assessed as disruption of PD-1/PD-L1 complex by measuring PD-L1 dimerization measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563738(CHEMBL4794941)
Affinity DataIC50: 1.68E+4nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin) assessed as disruption of PD-1/PD-L1 complex by measuring PD-L1 dimerization measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563740(CHEMBL4761045)
Affinity DataIC50: 2.29E+4nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin) assessed as disruption of PD-1/PD-L1 complex by measuring PD-L1 dimerization measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50563741(CHEMBL4780908)
Affinity DataIC50: 5.00E+6nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed