Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50012460
LigandPNGBDBM50317558(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]biphe...)
Affinity DataIC50: 117nMAssay Description:Antagonist activity at recombinant rat TRPM8 stably expressed in HEK293 cells assessed as inhibition of menthol-induced intracellular calcium level b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50532215(CBD-V | CBDV | Cannabidivarin | GWP42006)
Affinity DataEC50:  420nMAssay Description:Agonist activity at recombinant rat TRPA1 stably expressed in HEK293 cells assessed as increase in intracellular calcium release by Fluo-4AM dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50317558(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]biphe...)
Affinity DataIC50: 521nMAssay Description:Antagonist activity at recombinant rat TRPM8 stably expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50317558(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]biphe...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at recombinant human TRPM8 transiently expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux by whole-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50317558(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]biphe...)
Affinity DataIC50: 805nMAssay Description:Antagonist activity at recombinant human TRPM8 stably expressed in HEK293 cells assessed as inhibition of menthol-induced intracellular calcium level...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50532215(CBD-V | CBDV | Cannabidivarin | GWP42006)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at recombinant rat TRPM8 stably expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50317558(N-[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]biphe...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at recombinant human TRPM8 stably expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50557769(CHEMBL4777173)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at recombinant human TRPM8 transiently expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux by whole-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed