Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50013965
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50306710(CHEMBL1094759 | CHEMBL590494 | ((2R,3S,4R,5R)-3,4-...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571224(CHEMBL4860557)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571222(CHEMBL4871928)
Affinity DataEC50:  549nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571219(CHEMBL4847547)
Affinity DataEC50:  571nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571217(CHEMBL4866658)
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571214(CHEMBL4853338)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523545(CHEMBL4538320)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523526(CHEMBL3606064)
Affinity DataEC50:  203nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50319142(5-Iodouridine5'-Methylenediphosphate Triethylammon...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50271102(Uridine-5'-alpha,beta-methylene-diphosphate | 5'-O...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571224(CHEMBL4860557)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571223(CHEMBL4875403)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571222(CHEMBL4871928)
Affinity DataEC50:  549nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571221(CHEMBL4847697)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571220(CHEMBL4876940)
Affinity DataEC50:  1.67E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571219(CHEMBL4847547)
Affinity DataEC50:  571nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571217(CHEMBL4866658)
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571210(CHEMBL4846821)
Affinity DataEC50:  493nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571211(CHEMBL4862590)
Affinity DataEC50:  1.54E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571212(CHEMBL4866937)
Affinity DataEC50:  793nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50319142(5-Iodouridine5'-Methylenediphosphate Triethylammon...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523526(CHEMBL3606064)
Affinity DataEC50:  203nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523545(CHEMBL4538320)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571218(CHEMBL4874888)
Affinity DataEC50:  5.12E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523532(CHEMBL4457058)
Affinity DataEC50:  104nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523547(CHEMBL1198873)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523521(CHEMBL4299847)
Affinity DataEC50:  2.36E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571213(CHEMBL4853273)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571214(CHEMBL4853338)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571215(CHEMBL4863147)
Affinity DataEC50:  1.91E+3nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571216(CHEMBL4871088)
Affinity DataEC50:  902nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50271102(Uridine-5'-alpha,beta-methylene-diphosphate | 5'-O...)
Affinity DataIC50: 11nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571219(CHEMBL4847547)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571222(CHEMBL4871928)
Affinity DataIC50: 85nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523521(CHEMBL4299847)
Affinity DataIC50: 112nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50319142(5-Iodouridine5'-Methylenediphosphate Triethylammon...)
Affinity DataIC50: 162nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523547(CHEMBL1198873)
Affinity DataIC50: 257nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571223(CHEMBL4875403)
Affinity DataIC50: 321nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523526(CHEMBL3606064)
Affinity DataIC50: 362nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523526(CHEMBL3606064)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50271102(Uridine-5'-alpha,beta-methylene-diphosphate | 5'-O...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of rat CD73 using [3H]-AMP as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571224(CHEMBL4860557)
Affinity DataIC50: 6.66E+3nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50523545(CHEMBL4538320)
Affinity DataIC50: 1.66E+4nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571222(CHEMBL4871928)
Affinity DataIC50: 2.15E+4nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571219(CHEMBL4847547)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571217(CHEMBL4866658)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50571214(CHEMBL4853338)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human P2Y14 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed