Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50013000
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50562015(CHEMBL4778769)
Affinity DataEC50:  33nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50562016(CHEMBL4789628)
Affinity DataEC50:  62nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50562017(CHEMBL4790399)
Affinity DataEC50:  77nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50562018(CHEMBL4759021)
Affinity DataEC50:  50nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50562019(CHEMBL4791399)
Affinity DataEC50:  567nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50375593(CHEMBL408701)
Affinity DataEC50:  1.01E+3nMAssay Description:Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed