Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50011509
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50108664(1'-benzylspiro[3,4-dihydro-1H-isochromene-1,4'-(he...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 8 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50108653(1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromen...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 8 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548089(CHEMBL4761627)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548090(CHEMBL4792455)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver sigma 2 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548089(CHEMBL4761627)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver sigma 2 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548092(CHEMBL4797610)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50108664(1'-benzylspiro[3,4-dihydro-1H-isochromene-1,4'-(he...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver sigma 2 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548089(CHEMBL4761627)
Affinity DataKi:  150nMAssay Description:Binding affinity to DOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548091(CHEMBL4781486)
Affinity DataKi:  278nMAssay Description:Displacement of [3H]-pentazocine from guinea pig brain sigma 1 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548092(CHEMBL4797610)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver sigma 2 receptor incubated for 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548089(CHEMBL4761627)
Affinity DataKi:  407nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit�T M�Nster Corrensstr

Curated by ChEMBL
LigandPNGBDBM50548089(CHEMBL4761627)
Affinity DataKi:  696nMAssay Description:Binding affinity to MOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed