Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50017522
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataKd:  34nMAssay Description:Binding affinity to recombinant GST tagged STAT3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataKon:  0.0152M-1s-1Assay Description:Binding affinity to recombinant GST tagged STAT3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC in human MDA-MB-231 cells incubated for 24 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human HDAC6 using RHKK(Ac)AMC fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataIC50: 683nMAssay Description:Inhibition of recombinant human HDAC1 using RHKK(Ac)AMC fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed