Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50015079
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582589(CHEMBL5087765)
Affinity DataEC50:  2.22E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582580(CHEMBL5086432)
Affinity DataEC50:  3.57E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582581(CHEMBL5079696)
Affinity DataEC50:  7.33E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582582(CHEMBL5094868)
Affinity DataEC50:  360nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582583(CHEMBL5075407)
Affinity DataEC50:  330nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582584(CHEMBL5084935)
Affinity DataEC50:  2.35E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582585(CHEMBL5085416)
Affinity DataEC50:  820nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582586(CHEMBL5090439)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582587(CHEMBL5081498)
Affinity DataEC50:  180nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582588(CHEMBL5075033)
Affinity DataEC50:  140nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582579(CHEMBL5092504)
Affinity DataEC50:  7.13E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582590(CHEMBL5078772)
Affinity DataEC50:  2.82E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582591(CHEMBL5087088)
Affinity DataEC50:  3.05E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582592(CHEMBL5092787)
Affinity DataEC50:  39nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582593(CHEMBL5084309)
Affinity DataEC50:  48nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582594(CHEMBL5088133)
Affinity DataEC50:  35nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582595(CHEMBL5090848)
Affinity DataEC50:  1.73E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582596(CHEMBL5074635)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582560(CHEMBL5092725)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to recombinant human TLR2 expressed in H5 cells by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582597(CHEMBL5083746)
Affinity DataKd:  53nMAssay Description:Binding affinity to recombinant human TLR2 expressed in H5 cells by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582570(CHEMBL1608279)
Affinity DataEC50:  2.85E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582561(CHEMBL5076778)
Affinity DataEC50:  1.19E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582562(CHEMBL5073453)
Affinity DataEC50:  1.21E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582563(CHEMBL5081426)
Affinity DataEC50:  1.46E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582564(CHEMBL5088017)
Affinity DataEC50:  7.60E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582565(CHEMBL5093674)
Affinity DataEC50:  5.84E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582566(CHEMBL5075248)
Affinity DataEC50:  1.41E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582567(CHEMBL5087280)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582568(CHEMBL5086140)
Affinity DataEC50:  1.47E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582569(CHEMBL3827142)
Affinity DataEC50:  2.65E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582560(CHEMBL5092725)
Affinity DataEC50:  1.17E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582571(CHEMBL5093471)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582572(CHEMBL5080644)
Affinity DataEC50:  8.77E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582573(CHEMBL5084965)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582574(CHEMBL5092135)
Affinity DataEC50:  4.73E+3nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582575(CHEMBL1522109)
Affinity DataEC50:  1.33E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582576(CHEMBL5091448)
Affinity DataEC50:  1.21E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582577(CHEMBL5077518)
Affinity DataEC50:  3.39E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50582578(CHEMBL5083799)
Affinity DataEC50:  1.19E+4nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed