Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50015628
TargetTyrosine-protein kinase SYK(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAurora kinase A(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Aurora A(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587898(CHEMBL5195433)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of BRAF V599E mutant(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 14nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 84nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 179nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 283nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAromatase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus insect cell using 7-methoxy-trifluoromethyl coumarin (MFC) as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587903(CHEMBL5206722)
Affinity DataIC50: 910nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587900(CHEMBL5190487)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587902(CHEMBL5185543)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50236238(5beta-cholanic acid-3alpha-ol | CHEMBL1478 | (3alp...)
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587899(CHEMBL5190025)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587903(CHEMBL5206722)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587901(CHEMBL5179597)
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50236238(5beta-cholanic acid-3alpha-ol | CHEMBL1478 | (3alp...)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50014846(7alphaH-colchicine | (S)-N-(5,6,7,9-tetrahydro-1,2...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587901(CHEMBL5179597)
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587902(CHEMBL5185543)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of ERalpha (unknown origin) in MCF7 cells measured after 24 to 48 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587900(CHEMBL5190487)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of TCPTP (unknown origin) by SpectraMax 340 microplate reader AnalysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50587904(CHEMBL5185200)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of ERalpha (unknown origin) in MCF7 cells measured after 24 to 48 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed