Report error Found 105 Enz. Inhib. hit(s) with all data for entry = 50013947
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional a...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional a...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 109nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional ac...More data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 122nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 128nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional ac...More data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional ac...More data for this Ligand-Target Pair
Affinity DataKi: 153nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataKi: 181nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 186nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 208nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 246nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 261nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 347nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 415nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataKi: 453nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 534nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 554nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 633nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional ac...More data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 674nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 705nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 721nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 969nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional ac...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional a...More data for this Ligand-Target Pair
Affinity DataKi: 1.29E+3nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HEK293T cells assessed as transcriptional activities by measuring ERE driven reporter ...More data for this Ligand-Target Pair

3D Structure (crystal)
























