Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50014994
TargetBifunctional epoxide hydrolase 2(Rat)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM409005(US10377744, Compound No. 26 | US11123311, Compound...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50217448(trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]b...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581720(CHEMBL5080024 | US20240182406, Example C4)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50217448(trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]b...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581722(CHEMBL5081815 | US20240182406, Example C1)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50217448(trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]b...)
Affinity DataIC50: 8nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50191854(N-(1-acetyl-piperidin-4-yl)-N'-(adamantan-1-yl)ure...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50560744(CHEMBL4779073)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581721(CHEMBL5083623)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50560745(CHEMBL4797443)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581726(CHEMBL5084924)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50560743(CHEMBL4759592)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581718(CHEMBL5090478)
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581723(CHEMBL5083763)
Affinity DataIC50: 941nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant CYP2C19 preincubated for 5 mins in presence of NADP+ by fluorescent assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant CYP2C19 preincubated for 5 mins in presence of NADP+ by fluorescent assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581724(CHEMBL5094924)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581719(CHEMBL5083283)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LOX-5 preincubated for 10 mins in presence of AA and ATP measured after 20 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LOX-5 preincubated for 10 mins in presence of AA and ATP measured after 20 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LOX-5 preincubated for 10 mins in presence of AA and ATP measured after 20 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed