Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015414
TargetDNA topoisomerase 2-alpha(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586362(CHEMBL5083245)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human TOP2A assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586362(CHEMBL5083245)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human TOP2B assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586360(DEXRAZOXANE | CHEBI:50223 | Dexrazoxane | Razoxane...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human TOP2A assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586360(DEXRAZOXANE | CHEBI:50223 | Dexrazoxane | Razoxane...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human TOP2B assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586361(CHEMBL5076925)
Affinity DataIC50: 3.01E+5nMAssay Description:Inhibition of human TOP2A assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50586361(CHEMBL5076925)
Affinity DataIC50: 5.05E+5nMAssay Description:Inhibition of human TOP2B assessed as reduction in relaxation of supercoiled DNA using kDNA as substrate incubated for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed