Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50015604
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  0.0850nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(7-36) induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(9-36) induced cAMP accumulation in presence of IBMXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  7nMAssay Description:Positive allosteric modulator activity at human GLP-1R transfected in rat INS-1 832/13 cells assessed as potentiation of GLP-1(9-36) induced cAMP acc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human GLP-1R expressed in CHO-K1 cells assessed as potentiation of GLP-1(9-36) induced beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587765(CHEMBL5191256)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587762(CHEMBL5197819)
Affinity DataEC50:  24nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  270nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587761(CHEMBL5206162)
Affinity DataEC50:  800nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587764(CHEMBL5198772)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of EC20 GLP-1(9-36) induced cAMP accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50587763(CHEMBL5183336)
Affinity DataEC50:  1.80E+3nMAssay Description:Partial agonist activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(9-36) induced cAMP accumulation in presence of I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed