Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50015885
TargetThymidylate synthase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590309(CHEMBL5196526)
Affinity DataKd:  4.40E+4nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetThymidylate synthase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590310(CHEMBL5195943)
Affinity DataKd:  1.20E+5nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetThymidylate synthase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590309(CHEMBL5196526)
Affinity DataKi:  4.00E+4nMAssay Description:Non competitive type inhibition of human TS assessed as inhibition constant using varying levels of mTHF as substrate by UV-Vis spectroscopy based an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetThymidylate synthase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590310(CHEMBL5195943)
Affinity DataKi:  7.30E+4nMAssay Description:Non competitive type inhibition of human TS assessed as inhibition constant using varying levels of mTHF as substrate by UV-Vis spectroscopy based an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed