Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50013728
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569052(CHEMBL4866400)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human ASAH2 using RBM14C24 fluorogenic substrate measured at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569052(CHEMBL4866400)
Affinity DataIC50: 366nMAssay Description:Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at pH 7.5 by fluorescence sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human ASAH1 stably over expressed in human intact A-375 cells using RBM14C12 fluorogenic substrate measured at pH 4.5 by fluorescence s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAcid ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human ASAH1 stably over expressed in human intact A-375 cells using RBM14C12 fluorogenic substrate measured at pH 4.5 by fluorescence s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569050(CHEMBL4848172)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569051(CHEMBL4865548)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataKi:  3.60E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeutral ceramidase(Human)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataKi:  5.40E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAlkaline ceramidase 3(Mouse)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataKi:  2.55E+4nMAssay Description:Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAlkaline ceramidase 3(Mouse)
Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataKi:  3.44E+4nMAssay Description:Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed