Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50013166
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563327(CHEMBL4754754)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human N- terminal His-tagged GGPPS (1 to 300 residues) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563326(CHEMBL4759010)
Affinity DataIC50: 173nMAssay Description:Inhibition of recombinant human N- terminal His-tagged GGPPS (1 to 300 residues) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563330(CHEMBL4749465)
Affinity DataIC50: 750nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563331(CHEMBL4754564)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563331(CHEMBL4754564)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563330(CHEMBL4749465)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563330(CHEMBL4749465)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563334(CHEMBL4750458)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563334(CHEMBL4750458)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563329(CHEMBL4752134)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563334(CHEMBL4750458)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563329(CHEMBL4752134)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563329(CHEMBL4752134)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563327(CHEMBL4754754)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563326(CHEMBL4759010)
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563333(CHEMBL4778936)
Affinity DataIC50: 9.53E+4nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563332(CHEMBL4756107)
Affinity DataIC50: 9.79E+4nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563336(CHEMBL4783284)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563335(CHEMBL4763150)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563333(CHEMBL4778936)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563331(CHEMBL4754564)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563337(CHEMBL4764230)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563337(CHEMBL4764230)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563336(CHEMBL4783284)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563335(CHEMBL4763150)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563333(CHEMBL4778936)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563332(CHEMBL4756107)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563337(CHEMBL4764230)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563336(CHEMBL4783284)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563335(CHEMBL4763150)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563332(CHEMBL4756107)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed