Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50012402
Affinity DataIC50: 0.460nMAssay Description:Inhibition of C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) expressed in Sf9 cells using Ac-peptide as substrate preincubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) expressed in Sf9 cells using Ac-peptide as substrate preincubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate and trypsin addition an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate and trypsin addition an...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate preincubated fo...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 16nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate and trypsin addition and further incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human HDAC6 using Ac-peptide as substrate preincubated for 15 mins followed by substrate and trypsin addition and further incubated for...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human C-terminal His-tagged SIRT2 (50 to 356 residues) expressed in Escherichia coli using Ac-peptide as substrate preincubated for 15 ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human C-terminal His-tagged SIRT2 (50 to 356 residues) expressed in Escherichia coli using Ac-peptide as substrate preincubated for 15 ...More data for this Ligand-Target Pair
