Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50012691
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKd: 340nMAssay Description:Displacement of (1-(2-aminoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)(4-((1-neopentyl-1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)methanone from FNTA in...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 475nMAssay Description:Displacement of (1-(2-aminoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)(4-((1-neopentyl-1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)methanone from FNTB in...More data for this Ligand-Target Pair
Affinity DataKd: 1.90E+4nMAssay Description:Displacement of (1-(2-aminoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)(4-((1-neopentyl-1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)methanone from AFG3L2 ...More data for this Ligand-Target Pair
Affinity DataKd: 1.90E+4nMAssay Description:Displacement of (1-(2-aminoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)(4-((1-neopentyl-1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)methanone from NMRAL1 ...More data for this Ligand-Target Pair
