Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50013128
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562872(CHEMBL4787131)
Affinity DataIC50: 10nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562872(CHEMBL4787131)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562870(CHEMBL4796584)
Affinity DataIC50: 15nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562870(CHEMBL4796584)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562871(CHEMBL4755763)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562871(CHEMBL4755763)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed