Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50011991
TargetMaternal embryonic leucine zipper kinase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataEC50:  2.11E+4nMAssay Description:Displacement of kinase tracer 236 from human N-terminal His-tagged MELK (1 to 337 residues) expressed in Escherichia coli BL21 pLysS by microscale th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataIC50: 9.48E+3nMAssay Description:Inhibition of MELK (unknown origin) using FRET-peptide as substrate incubated for 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of RSK2 (unknown origin) using FRET-peptide as substrate incubated for 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of JAK2 (unknown origin) using FRET-peptide as substrate incubated for 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of MST3 (unknown origin) using FRET-peptide as substrate incubated for 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ERK2 (unknown origin) using FRET-peptide as substrate incubated for 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50553103(CHEMBL4784866)
Affinity DataKi:  5.47E+3nMAssay Description:Displacement of kinase tracer 236 from human N-terminal His-tagged MELK (1 to 337 residues) expressed in Escherichia coli BL21 pLysS by microscale th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed