Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50011503
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM396236(6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548078(CHEMBL4746798)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548079(CHEMBL4754865)
Affinity DataIC50: 0.0660nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548076(CHEMBL4781133 | US11583532, Example 5.1)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548077(CHEMBL4789143)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548065(CHEMBL4785875)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548065(CHEMBL4785875)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548066(CHEMBL4791105)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548063(CHEMBL4741413)
Affinity DataIC50: 6nMAssay Description:Inhibition of GOAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548066(CHEMBL4791105)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548069(CHEMBL4741670)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548075(CHEMBL4764363 | US11312709, Example 1a)
Affinity DataIC50: 50nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using biotinylated ghrelin peptide/octanoyl-CoA/palmitoyl CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM367610(US10227310, Example 2 | N-[(1S)-2-[4-[2- (4-Amino-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548061(CHEMBL4741216)
Affinity DataIC50: 69nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM289086(US10093651, Example 2 | N-[(1 S)-2-[4-[2-[4-Amino-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM367612(US10227310, Example 42 | N-[(1S)-2-[4-[2-(4-Amino-...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM367615(US10227310, Example 71 | Methyl N-[(1S)-2-[4-[2-(4...)
Affinity DataIC50: 149nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548062(CHEMBL4742847)
Affinity DataIC50: 192nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50094876(CHEMBL3589129)
Affinity DataIC50: 700nMAssay Description:Inhibition of GOAT (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548072(CHEMBL4778987)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548074(CHEMBL4750990)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548068(CHEMBL4753228)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using ghrelin(1 to 5) pentapeptide as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM217380(CDDO-EA, 3)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human GOAT expressed in baculovirus infected sf9 insect cell membrane using GSSFLC-acrylodan and octanoyl-CoA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548064(CHEMBL4787843)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human GOAT expressed in baculovirus infected sf9 insect cell membrane using GSSFLC-acrylodan and octanoyl-CoA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548067(CHEMBL4762372)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using ghrelin(1 to 5) pentapeptide as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548073(CHEMBL4756686)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548070(CHEMBL4784392)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGhrelin O-acyltransferase(Mouse)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548071(CHEMBL4788110)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50548063(CHEMBL4741413)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GHSR-1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed