Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50012385
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557258(CHEMBL4796216)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50241203(exenatide | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPP...)
Affinity DataEC50:  0.0160nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557260(CHEMBL4741000)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557263(CHEMBL4752195)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at rat GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataEC50:  0.480nMAssay Description:Agonist activity at rat GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557263(CHEMBL4752195)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557260(CHEMBL4741000)
Affinity DataEC50:  0.533nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557259(CHEMBL4748874)
Affinity DataEC50:  0.473nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50241203(exenatide | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPP...)
Affinity DataIC50: 6nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557258(CHEMBL4796216)
Affinity DataIC50: 7.10nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataIC50: 10nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50466532(CHEMBL4281479)
Affinity DataIC50: 12nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50197025(PYY(3-36) | CHEMBL439904)
Affinity DataIC50: 16nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataIC50: 18nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557263(CHEMBL4752195)
Affinity DataIC50: 25nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataIC50: 27nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50: 28nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50: 32nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50: 41nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557259(CHEMBL4748874)
Affinity DataIC50: 47nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557260(CHEMBL4741000)
Affinity DataIC50: 61nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataIC50: 82nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataIC50: 113nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557258(CHEMBL4796216)
Affinity DataIC50: 300nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557260(CHEMBL4741000)
Affinity DataIC50: 321nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557263(CHEMBL4752195)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed