Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50013693
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chr...)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chr...)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chr...)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(CHEMBL78010 | 5,7-dihydroxy-6-methoxy-2-(4-methoxy...)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(CHEMBL78010 | 5,7-dihydroxy-6-methoxy-2-(4-methoxy...)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(CHEMBL78010 | 5,7-dihydroxy-6-methoxy-2-(4-methoxy...)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50344054(3',5-dihydroxy-4',6,7-trimethoxy flavone | 6-metho...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50187658(7-O-methylapigenin | genkwanin | 5-hydroxy-2-(4-hy...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed