Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50012686
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029838(3-[5-(4-Benzyloxy-phenyl)-2-thioxo-[1,3,4]oxadiazo...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029838(3-[5-(4-Benzyloxy-phenyl)-2-thioxo-[1,3,4]oxadiazo...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029834(5-(4-Benzyloxy-phenyl)-3-(2-hydroxy-ethyl)-3H-[1,3...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029834(5-(4-Benzyloxy-phenyl)-3-(2-hydroxy-ethyl)-3H-[1,3...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50559391(CHEMBL4790891)
Affinity DataIC50: 56nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate by radioassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50559390(CHEMBL4792372)
Affinity DataIC50: 74nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate by radioassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50559391(CHEMBL4790891)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-A using [14C]-5-HT as substrate by radioassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50559390(CHEMBL4792372)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-A using [14C]-5-HT as substrate by radioassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Medical University-Sofia

Curated by ChEMBL
LigandPNGBDBM50029825(3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...)
Affinity DataKi:  220nMAssay Description:Competitive inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed