Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50012170
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554895(CHEMBL4776750)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract after 30 mins using F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554894(CHEMBL4782402)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged prephosphorylated Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554895(CHEMBL4776750)
Affinity DataKd:  21nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged prephosphorylated Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  21nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract by isothermal titrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract by isothermal titrati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged prephosphorylated Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKd:  705nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged prephosphorylated Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554894(CHEMBL4782402)
Affinity DataKd:  20nMAssay Description:Binding affinity to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract after 30 mins using F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554899(CHEMBL4793963)
Affinity DataKi:  160nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554903(CHEMBL4741554)
Affinity DataKi:  210nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554899(CHEMBL4793963)
Affinity DataKi:  320nMAssay Description:Inhibition of FAM-Bim peptide binding to MCl1 (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554903(CHEMBL4741554)
Affinity DataKi:  350nMAssay Description:Inhibition of FAM-Bim peptide binding to MCl1 (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50505362(CHEMBL4470807)
Affinity DataKi:  490nMAssay Description:Inhibition of FAM-Bim peptide binding to MCl1 (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554903(CHEMBL4741554)
Affinity DataKi:  550nMAssay Description:Inhibition of FAM-Bim peptide binding to Bcl-xl (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554900(CHEMBL4785269)
Affinity DataKi:  560nMAssay Description:Inhibition of FAM-Bim peptide binding to MCl1 (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50505362(CHEMBL4470807)
Affinity DataKi:  750nMAssay Description:Inhibition of FAM-Bim peptide binding to Bcl-xl (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554896(CHEMBL4791005)
Affinity DataKi:  780nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554901(CHEMBL4748002)
Affinity DataKi:  810nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554899(CHEMBL4793963)
Affinity DataKi:  810nMAssay Description:Inhibition of FAM-Bim peptide binding to Bcl-xl (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50505362(CHEMBL4470807)
Affinity DataKi:  850nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554898(CHEMBL4799995)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554900(CHEMBL4785269)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554900(CHEMBL4785269)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to Bcl-xl (unknown origin) measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50303802(CHEMBL4169380)
Affinity DataKi:  1.27E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554897(CHEMBL4777045)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50554902(CHEMBL4764983)
Affinity DataKi:  4.32E+3nMAssay Description:Inhibition of FAM-Bim peptide binding to human full-length N-terminal His6-tagged Bcl2 (2 to 206 residues) expressed in Escherichia coli S12 extract ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed