Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017347
TargetHistone deacetylase(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50601389(CHEMBL5189571)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 250nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50: 780nMAssay Description:Inhibition of CDK2 in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50: 870nMAssay Description:Inhibition of CDK3 in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of CDK1 in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKi:  0.0160nMAssay Description:Binding affinity to Src (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSphingosine kinase 2(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50312869(N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity to Sphk2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50312869(N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to Sphk1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed