Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50018383
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244285(CHEMBL4079520)
Affinity DataIC50: 700nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244286(CHEMBL4100917)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244285(CHEMBL4079520)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human CB2 receptor stably expressed in HEK cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607948(CHEMBL5270707)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607945(CHEMBL5285808)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to human CB2 receptor stably expressing HEK cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor (unknown origin) expressed in HEK cell membrane measured after 90 mins by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human recombinant CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607944(CHEMBL5281620)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607947(CHEMBL1338358)
Affinity DataKi:  14nMAssay Description:Binding affinity to CB2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607946(CHEMBL5269105)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]HU-243 binding to CB2 receptor in human COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataKi:  37nMAssay Description:Binding affinity to human CB2 receptor stably expressed in HEK cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607948(CHEMBL5270707)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataKi:  188nMAssay Description:Binding affinity to human CB2 receptor stably expressed in HEK cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607947(CHEMBL1338358)
Affinity DataKi:  383nMAssay Description:Binding affinity to CB1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244286(CHEMBL4100917)
Affinity DataKi:  426nMAssay Description:Binding affinity to human CB2 receptor stably expressed in HEK cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor (unknown origin) expressed in CHO cell membrane measured after 90 mins by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607945(CHEMBL5285808)
Affinity DataKi:  677nMAssay Description:Displacement of [3H]CP55940 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 1 hr by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  1.92E+3nMAssay Description:Binding affinity to human recombinant CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607944(CHEMBL5281620)
Affinity DataKi:  2.29E+3nMAssay Description:Displacement of [3H]CP55940 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 1 hr by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to human CB1 receptor stably expressing CHO cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50607946(CHEMBL5269105)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]HU-243 from rat brain membrane CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed