Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50011443
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547684(CHEMBL4740067)
Affinity DataIC50: 30nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM109086(US8604016, 670 | US9938267, Cmpd ID 670 | US107935...)
Affinity DataIC50: 50nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547673(CHEMBL4786465)
Affinity DataIC50: 50nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547682(CHEMBL4751180)
Affinity DataIC50: 80nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547679(CHEMBL4778536)
Affinity DataIC50: 100nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547675(CHEMBL4759659)
Affinity DataIC50: 110nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547676(CHEMBL4777997)
Affinity DataIC50: 140nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US8604016, 1 | US9938267, Cmpd ID ...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human kidney glutaminase assessed as reduction in glutamate production in presence of NADPH-dependent glutamate dehydrogenase preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547677(CHEMBL4783740)
Affinity DataIC50: 200nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50503307(CHEMBL4466771)
Affinity DataIC50: 280nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547674(CHEMBL4745259)
Affinity DataIC50: 1.60E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50: 2.30E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547678(CHEMBL4747169)
Affinity DataIC50: 3.00E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US8604016, 1 | US9938267, Cmpd ID ...)
Affinity DataIC50: 3.30E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547683(CHEMBL4756837)
Affinity DataIC50: 6.80E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547681(CHEMBL4753483)
Affinity DataIC50: 1.40E+4nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108575(US8604016, 145 | US9938267, Cmpd ID 145)
Affinity DataIC50: 1.00E+5nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50547680(CHEMBL4747582)
Affinity DataIC50: 1.00E+5nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed