Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50012931
TargetGTPase KRas(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50561645(CHEMBL4760058)
Affinity DataKd:  430nMAssay Description:Binding affinity to wild type KRAS (unknown origin) using FAM-labelled peptide as substrate in absence of Tween20 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50561645(CHEMBL4760058)
Affinity DataKd:  430nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) using FAM-labelled peptide as substrate in absence of Tween20 by fluorescence polarization assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataKd:  21nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataKd:  16nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) using FAM-labelled peptide as substrate in presence of Tween20 by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed