Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50013017
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562162(CHEMBL4753047)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562163(CHEMBL4741685)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562164(CHEMBL4747132)
Affinity DataEC50:  740nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562165(CHEMBL4746964)
Affinity DataEC50:  7.60E+3nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562166(CHEMBL4758738)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562167(CHEMBL4762018)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562168(CHEMBL4755001)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562169(CHEMBL4761277)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562170(CHEMBL4785785)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562171(CHEMBL4760112)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562172(CHEMBL4746765)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50527040(LJN-452 | LJN452 | NVP-LJN452-NXA | Tropifexor)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed