Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50012905
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50264106(CHEMBL3818875)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561492(CHEMBL4800490)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561490(CHEMBL4746942)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561486(CHEMBL4759111)
Affinity DataIC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561483(CHEMBL4795110)
Affinity DataIC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561482(CHEMBL4764099)
Affinity DataIC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561489(CHEMBL4745687)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561491(CHEMBL4755533)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561488(CHEMBL4745452)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561484(CHEMBL4778283)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561495(CHEMBL4794423)
Affinity DataIC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561494(CHEMBL4751593)
Affinity DataIC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561487(CHEMBL4759652)
Affinity DataIC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561480(CHEMBL4791222)
Affinity DataIC50: 4nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561493(CHEMBL4747688)
Affinity DataIC50: 5nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561474(CHEMBL4746544)
Affinity DataIC50: 5nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561485(CHEMBL4757630)
Affinity DataIC50: 7nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561473(CHEMBL4753882)
Affinity DataIC50: 11nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561472(CHEMBL4797528)
Affinity DataIC50: 12nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561478(CHEMBL4741953)
Affinity DataIC50: 16nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561471(CHEMBL4781282)
Affinity DataIC50: 22nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561481(CHEMBL4746074)
Affinity DataIC50: 29nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561479(CHEMBL4782144)
Affinity DataIC50: 40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561468(CHEMBL4745567)
Affinity DataIC50: 50nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561469(CHEMBL4754077)
Affinity DataIC50: 60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561470(CHEMBL4763763)
Affinity DataIC50: 60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50029781((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...)
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561464(CHEMBL4793032)
Affinity DataIC50: 90nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561489(CHEMBL4745687)
Affinity DataIC50: 96nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561485(CHEMBL4757630)
Affinity DataIC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561493(CHEMBL4747688)
Affinity DataIC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561492(CHEMBL4800490)
Affinity DataIC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561486(CHEMBL4759111)
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50511324(CHEMBL4529780)
Affinity DataIC50: 130nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561484(CHEMBL4778283)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561494(CHEMBL4751593)
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561483(CHEMBL4795110)
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561492(CHEMBL4800490)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-HETE and LTB4 formation pre-incubated for 15 mins before addition of AA and A23187 and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561490(CHEMBL4746942)
Affinity DataIC50: 220nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561495(CHEMBL4794423)
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561491(CHEMBL4755533)
Affinity DataIC50: 260nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561482(CHEMBL4764099)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50144892(CHEMBL3764398)
Affinity DataIC50: 300nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561472(CHEMBL4797528)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561473(CHEMBL4753882)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561465(CHEMBL4792346)
Affinity DataIC50: 500nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561471(CHEMBL4781282)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561479(CHEMBL4782144)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561474(CHEMBL4746544)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50561466(CHEMBL4760881)
Affinity DataIC50: 600nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
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