Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50016035
TargetIntegrase(Human immunodeficiency virus type 1)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591631(CHEMBL5184817)
Affinity DataIC50: 18nMAssay Description:Inhibition of influenza A virus neuraminidase using 2-(4-methylumbelliferyl)-a-D-acetylneuraminic acid as substrate incubated for 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591630(CHEMBL5194590)
Affinity DataIC50: 78nMAssay Description:Inhibition of BACE1 (unknown origin) using beta-secretase as substrate incubated in dark for 1 hr by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50: 260nMAssay Description:Inhibition of BACE1 (unknown origin) using beta-secretase as substrate incubated in dark for 1 hr by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591609(CHEMBL4461886)
Affinity DataIC50: 640nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591614(CHEMBL5191384)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of COX-2 (unknown origin) by fluorescent inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591618(CHEMBL5197207)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant COX-2 pretreated with compound for 10 mins followed by substrate addition for 10 mins by fluorescent inhibitor screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591619(CHEMBL5189985)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant COX-2 pretreated with compound for 10 mins followed by substrate addition for 10 mins by fluorescent inhibitor screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591620(CHEMBL5202074)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant COX-2 pretreated with compound for 10 mins followed by substrate addition for 10 mins by fluorescent inhibitor screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591615(CHEMBL5193344)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of COX-2 (unknown origin) by fluorescent inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591616(CHEMBL5179776)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of COX-2 (unknown origin) by fluorescent inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591622(CHEMBL5208407)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of porcine pancreatic lipase using p-Nitrophenyl butyrate substrate incubated for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591617(CHEMBL5177548)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of COX-2 (unknown origin) by fluorescent inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591626(CHEMBL5201538)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of DDR1 (unknown origin) by lanthascreen eu kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591611(CHEMBL5200956)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate incubated for 20 mins by DTNB reagent based spectrophotometric metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591623(CHEMBL5173849)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of DDR1 (unknown origin) by lanthascreen eu kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591610(CHEMBL5197965)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate incubated for 20 mins by DTNB reagent based spectrophotometric metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591613(CHEMBL5204848)
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591623(CHEMBL5173849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591624(CHEMBL5172432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591625(CHEMBL5183728)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589176(CHEMBL5194876)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591612(CHEMBL5180809)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591621(CHEMBL5173192)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-Nitrophenyl butyrate substrate incubated for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591621(CHEMBL5173192)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of porcine pancreatic lipase using p-Nitrophenyl butyrate substrate incubated for 15 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591628(CHEMBL5207225)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591629(CHEMBL5183150)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50591627(CHEMBL5191899)
Affinity DataIC50: 7.16E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed