Compile Data Set for Download or QSAR
Report error Found 110 Enz. Inhib. hit(s) with all data for entry = 50012323
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556541(CHEMBL4756103)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataEC50:  586nMAssay Description:Agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataEC50:  0.360nMAssay Description:Antagonist activity at human CB1R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  270nMAssay Description:Antagonist activity at human CB1R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataEC50:  120nMAssay Description:Partial agonist activity at human CB1R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556541(CHEMBL4756103)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataEC50:  17nMAssay Description:Inverse agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataEC50:  6.5nMAssay Description:Inverse agonist activity at human CB2R expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  170nMAssay Description:Antagonist activity at human CB2R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  81nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  192nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  711nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  102nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  62nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataEC50:  103nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataIC50: 530nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataIC50: 530nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556543(CHEMBL4753784)
Affinity DataIC50: 530nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataIC50: 560nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetLysophosphatidylserine lipase ABHD12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556538(CHEMBL4740330)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556539(CHEMBL4750323)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556540(CHEMBL4740428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556541(CHEMBL4756103)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556543(CHEMBL4753784)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556544(CHEMBL4792271)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556537(CHEMBL4757488)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556538(CHEMBL4740330)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
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