Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50011365
LigandPNGBDBM50547421(CHEMBL4753214)
Affinity DataEC50:  670nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547425(CHEMBL4789662)
Affinity DataEC50:  140nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547424(CHEMBL4778128)
Affinity DataEC50:  200nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547423(CHEMBL4761586)
Affinity DataEC50:  120nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547413(CHEMBL4787520)
Affinity DataEC50:  960nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547412(CHEMBL4751235)
Affinity DataEC50:  350nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547411(CHEMBL4793528)
Affinity DataEC50:  2.01E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547410(CHEMBL4785740)
Affinity DataEC50:  2.66E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547422(CHEMBL4762232)
Affinity DataEC50:  300nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547426(CHEMBL4744474)
Affinity DataEC50:  160nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547420(CHEMBL4781791)
Affinity DataEC50:  700nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547419(CHEMBL4800006)
Affinity DataEC50:  270nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547418(CHEMBL4740085)
Affinity DataEC50:  110nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547409(CHEMBL4752570)
Affinity DataEC50:  310nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547437(CHEMBL4784447)
Affinity DataEC50:  4.60E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547407(CHEMBL4751262)
Affinity DataEC50:  2.04E+4nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547408(CHEMBL4763259)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547427(CHEMBL4789308)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547428(CHEMBL4761962)
Affinity DataEC50:  1.80E+4nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547414(CHEMBL4751496)
Affinity DataEC50:  4.30E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547429(CHEMBL4755974)
Affinity DataEC50:  2.00E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547430(CHEMBL4753045)
Affinity DataEC50:  7.30E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547415(CHEMBL4779699)
Affinity DataEC50:  1.71E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547431(CHEMBL4778917)
Affinity DataEC50:  5.46E+5nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547432(CHEMBL4752891)
Affinity DataEC50:  4.70E+4nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547433(CHEMBL4740488)
Affinity DataEC50:  9.00E+4nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547434(CHEMBL4797904)
Affinity DataEC50:  8.82E+5nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547416(CHEMBL4759918)
Affinity DataEC50:  300nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547435(CHEMBL4758823)
Affinity DataEC50:  8.70E+4nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547436(CHEMBL4788234)
Affinity DataEC50:  1.17E+5nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547435(CHEMBL4758823)
Affinity DataEC50:  1.40E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production in presence of ODQ by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547417(CHEMBL4793885)
Affinity DataEC50:  270nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547407(CHEMBL4751262)
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547430(CHEMBL4753045)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547428(CHEMBL4761962)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547429(CHEMBL4755974)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547417(CHEMBL4793885)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547420(CHEMBL4781791)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547436(CHEMBL4788234)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547427(CHEMBL4789308)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547412(CHEMBL4751235)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50547435(CHEMBL4758823)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547416(CHEMBL4759918)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547414(CHEMBL4751496)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547433(CHEMBL4740488)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547431(CHEMBL4778917)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547415(CHEMBL4779699)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547432(CHEMBL4752891)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547422(CHEMBL4762232)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50547413(CHEMBL4787520)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
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