Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50012074
LigandChemical structure of BindingDB Monomer ID 50553900BDBM50553900(CHEMBL4750616)
Affinity DataIC50: 28nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553900BDBM50553900(CHEMBL4750616)
Affinity DataIC50: 30nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553945BDBM50553945(CHEMBL4790034)
Affinity DataIC50: 30nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553944BDBM50553944(CHEMBL4780624)
Affinity DataIC50: 33nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553944BDBM50553944(CHEMBL4780624)
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553944BDBM50553944(CHEMBL4780624)
Affinity DataIC50: 160nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553945BDBM50553945(CHEMBL4790034)
Affinity DataIC50: 200nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553945BDBM50553945(CHEMBL4790034)
Affinity DataIC50: 370nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553903BDBM50553903(CHEMBL4741204)
Affinity DataIC50: 450nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553938BDBM50553938(CHEMBL4762524)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553936BDBM50553936(CHEMBL4764722)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553935BDBM50553935(CHEMBL4795765)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553912BDBM50553912(CHEMBL4795130)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553904BDBM50553904(CHEMBL4760323)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553913BDBM50553913(CHEMBL4786342)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553933BDBM50553933(CHEMBL4757554)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553932BDBM50553932(CHEMBL4794211)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553934BDBM50553934(CHEMBL4799541)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553905BDBM50553905(CHEMBL4795430)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553900BDBM50553900(CHEMBL4750616)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553920BDBM50553920(CHEMBL4789355)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553942BDBM50553942(CHEMBL4760013)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553937BDBM50553937(CHEMBL4746193)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553941BDBM50553941(CHEMBL4786071)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553943BDBM50553943(CHEMBL4744586)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553930BDBM50553930(CHEMBL4757956)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553940BDBM50553940(CHEMBL4748876)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553911BDBM50553911(CHEMBL4764712)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553928BDBM50553928(CHEMBL4744726)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553909BDBM50553909(CHEMBL4745189)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553908BDBM50553908(CHEMBL4756014)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553907BDBM50553907(CHEMBL4749848)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553939BDBM50553939(CHEMBL4740907)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553906BDBM50553906(CHEMBL4748564)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553902BDBM50553902(CHEMBL4797667)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553901BDBM50553901(CHEMBL4786282)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553931BDBM50553931(CHEMBL4762837)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553929BDBM50553929(CHEMBL4742164)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553927BDBM50553927(CHEMBL4750067)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553926BDBM50553926(CHEMBL4741383)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553925BDBM50553925(CHEMBL1980395)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553924BDBM50553924(CHEMBL4764240)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553923BDBM50553923(CHEMBL4749410)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553922BDBM50553922(CHEMBL4783425)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553921BDBM50553921(CHEMBL4797478)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553919BDBM50553919(CHEMBL4765040)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553918BDBM50553918(CHEMBL4744580)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553917BDBM50553917(CHEMBL4755720)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553916BDBM50553916(CHEMBL4784022)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50553915BDBM50553915(CHEMBL4754580)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
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