Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50012887
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.0220nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561301(CHEMBL4751119)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561302(CHEMBL4782490)
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataEC50: >10nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataEC50: >10nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561294(CHEMBL4778702)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561295(CHEMBL4741481)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561296(CHEMBL4761096)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561297(CHEMBL4752614)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561298(CHEMBL4745013)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561299(CHEMBL4754151)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561300(CHEMBL4744639)
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561301(CHEMBL4751119)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561302(CHEMBL4782490)
Affinity DataEC50: >25nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561300(CHEMBL4744639)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561294(CHEMBL4778702)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561295(CHEMBL4741481)
Affinity DataEC50:  240nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561296(CHEMBL4761096)
Affinity DataEC50:  0.810nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561297(CHEMBL4752614)
Affinity DataEC50:  21nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561298(CHEMBL4745013)
Affinity DataEC50:  16nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561299(CHEMBL4754151)
Affinity DataEC50:  490nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561300(CHEMBL4744639)
Affinity DataEC50:  9nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561301(CHEMBL4751119)
Affinity DataEC50:  14nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561302(CHEMBL4782490)
Affinity DataEC50:  0.0290nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50152627(2-(4-Hydroxy-phenyl)-benzofuran-5-ol | 2-(4-HYDROX...)
Affinity DataEC50:  5.70nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50152624(5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBO...)
Affinity DataEC50:  1.90nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol | 2-(4-Hydr...)
Affinity DataEC50:  47nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50154045(5-hydroxy-2-(4-hydroxyphenyl)benzo[d]oxazole-7-car...)
Affinity DataEC50:  5.5nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.210nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50187243(ethinyloestradiol | 17alpha-ethynylestra-1,3,5(10)...)
Affinity DataEC50:  0.370nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  6nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561294(CHEMBL4778702)
Affinity DataEC50:  15nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561295(CHEMBL4741481)
Affinity DataEC50:  360nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561296(CHEMBL4761096)
Affinity DataEC50:  0.650nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561297(CHEMBL4752614)
Affinity DataEC50:  12nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561298(CHEMBL4745013)
Affinity DataEC50:  50nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561299(CHEMBL4754151)
Affinity DataEC50:  2.80E+3nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561300(CHEMBL4744639)
Affinity DataEC50:  78nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561301(CHEMBL4751119)
Affinity DataEC50:  51nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561302(CHEMBL4782490)
Affinity DataEC50:  0.270nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561303(CHEMBL4747395)
Affinity DataEC50:  4.40E+3nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM17289(folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...)
Affinity DataEC50:  0.940nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  5nMAssay Description:Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Displayed 1 to 50 (of 64 total ) | Next | Last >>
Jump to: