Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50012875
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475984({(2R,3S,4R,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475978({(2R,3S,4R,5R)-5-[4-amino-3-(1H-pyrazol-4-ylsulfan...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476001({(2R,3S,4R,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476012([(2R,3S,4R,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476084({(2R,3R,4S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475993({(2R,3S,4R,5R)-5-[4-amino-3-(ethylsulfanyl)-1H-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475994({(2R,3S,4R,5R)-5-[4-amino-3-(benzylsulfanyl)-1H-py...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476126({(2R,3S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H-py...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475969({(2R,3S,4R,5R)-5-[4-amino-3-(difluoromethoxy)-1H-p...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476025({(2R,3S,4R,5R)-5-[4-amino-3-(phenylsulfanyl)-1H-py...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476049([(2R,3R,4S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfa...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476086([(2R,3R,4S,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476058({(2R,3R,4S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476042({(2R,3R,4S,5R)-5-[4-amino-3-(difluoromethoxy)-1H-p...)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476058({(2R,3R,4S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476145({(2R,3S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-pyraz...)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476086([(2R,3R,4S,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 51nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476117({(2R,3S,5R)-5-[4-amino-3-(ethylsulfanyl)-1H-pyrazo...)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476049([(2R,3R,4S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfa...)
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476084({(2R,3R,4S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476165({(2S,3S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H-py...)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM50561267(CHEMBL4754045)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476105({(2R,3S,5R)-5-[4-amino-3-(2,3-dihydro-1H-inden-5-y...)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476106([(2R,3S,5R)-5-{4-amino-3-[(2-fluoro-4-methylphenyl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475984({(2R,3S,4R,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 83nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM50561266(CHEMBL4740719)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476145({(2R,3S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-pyraz...)
Affinity DataIC50: 86nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475937([(2R,3S,4R,5R)-5-(4-amino-3-methoxy-1H-pyrazolo[3,...)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476150([(2R,3S,5R)-5-{4-amino-3-[(3-methylphenyl)sulfanyl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476140({(2R,3S,5R)-5-[4-amino-3-(difluoromethoxy)-1H-pyra...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476124([(2R,3S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfanyl...)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476164({(2S,3S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-pyraz...)
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476038({(2S,3S,4R,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476086([(2R,3R,4S,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 140nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476039({(2S,3R,4S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476126({(2R,3S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H-py...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476161({(2S,3S,5R)-5-[4-amino-3-(2,3-dihydro-1H-inden-5-y...)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475993({(2R,3S,4R,5R)-5-[4-amino-3-(ethylsulfanyl)-1H-pyr...)
Affinity DataIC50: 160nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475969({(2R,3S,4R,5R)-5-[4-amino-3-(difluoromethoxy)-1H-p...)
Affinity DataIC50: 162nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476048([(2R,3R,4S,5R)-5-(4-amino-3-methoxy-1H-pyrazolo[3,...)
Affinity DataIC50: 177nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476012([(2R,3S,4R,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 178nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476169([(2S,3S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfanyl...)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476049([(2R,3R,4S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfa...)
Affinity DataIC50: 198nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476084({(2R,3R,4S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 199nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476025({(2R,3S,4R,5R)-5-[4-amino-3-(phenylsulfanyl)-1H-py...)
Affinity DataIC50: 201nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476135([(2R,3S,5R)-5-(4-amino-3-methoxy-1H-pyrazolo[3,4-d...)
Affinity DataIC50: 249nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM475944([(2R,3S,4R,5R)-5-(4-amino-3-ethoxy-1H-pyrazolo[3,4...)
Affinity DataIC50: 255nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476019({(2R,3S,4R,5R)-5-[4-amino-3-(benzyloxy)-1H-pyrazol...)
Affinity DataIC50: 264nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476145({(2R,3S,5R)-5-[4-amino-3-(methylsulfanyl)-1H-pyraz...)
Affinity DataIC50: 280nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandPNGBDBM476001({(2R,3S,4R,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 284nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
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