Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50012060
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553757BDBM50553757(CHEMBL4746471)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553762BDBM50553762(CHEMBL4758608)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553754BDBM50553754(CHEMBL4746482)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553764BDBM50553764(CHEMBL4749423)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553763BDBM50553763(CHEMBL4785208)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553761BDBM50553761(CHEMBL4756857)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553753BDBM50553753(CHEMBL4799496)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553760BDBM50553760(CHEMBL4757188)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553759BDBM50553759(CHEMBL4760677)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400240BDBM400240(7-((1-(Cyclopropylmethyl)-5-fluoro-4-methyl-1H-ben...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526866BDBM50526866(CHEMBL4581355)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553765BDBM50553765(CHEMBL4754539)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553749BDBM50553749(CHEMBL4761336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553747BDBM50553747(CHEMBL4753738)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553758BDBM50553758(CHEMBL4800521)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553756BDBM50553756(CHEMBL4785991)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 400242BDBM400242(N-(6-(1H-Imidazol-1-yl)pyridin-3-yl)-3-(cyclopropy...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553745BDBM50553745(CHEMBL4785872)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553741BDBM50553741(CHEMBL4748984)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553755BDBM50553755(CHEMBL4794600)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553746BDBM50553746(CHEMBL4764668)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553752BDBM50553752(CHEMBL4796770)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553750BDBM50553750(CHEMBL4761610)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553742BDBM50553742(CHEMBL4759403)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553748BDBM50553748(CHEMBL4794167)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553751BDBM50553751(CHEMBL4759785)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553744BDBM50553744(CHEMBL4741416)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553743BDBM50553743(CHEMBL4760815)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553734BDBM50553734(CHEMBL4778552)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553740BDBM50553740(CHEMBL4776208)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553738BDBM50553738(CHEMBL4747349)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553739BDBM50553739(CHEMBL4585261)
Affinity DataKi:  319nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553735BDBM50553735(CHEMBL4792380)
Affinity DataKi:  459nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553736BDBM50553736(CHEMBL4798572)
Affinity DataKi:  972nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526866BDBM50526866(CHEMBL4581355)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553737BDBM50553737(CHEMBL4796860)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed