Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50018355
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481823(CHEMBL5285949)
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM191598(KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...)
Affinity DataIC50: 4nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 7nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50483926(CHEMBL5285505)
Affinity DataIC50: 9nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481821(CHEMBL5277129)
Affinity DataIC50: 9nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481822(CHEMBL5274997)
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50482594(CHEMBL5290962)
Affinity DataIC50: 17nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM195612(GSK467)
Affinity DataIC50: 26nMAssay Description:Inhibition of KDM5B (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)
Affinity DataIC50: 49nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481826(CHEMBL5268579)
Affinity DataIC50: 49nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 60nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481827(CHEMBL5269187)
Affinity DataIC50: 65nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 98nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50396019(CHEMBL2169917 | 4'-(phenethylcarbamoyl)-[2,2&#...)
Affinity DataIC50: 110nMAssay Description:Inhibition of KDM4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481824(CHEMBL5276370)
Affinity DataIC50: 184nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481820(CHEMBL5268613)
Affinity DataIC50: 203nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223319(KDOAM-29)
Affinity DataIC50: 270nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481827(CHEMBL5269187)
Affinity DataIC50: 300nMAssay Description:Inhibition of KDM5B in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 530nMAssay Description:Inhibition of KDM5B in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223317(KDOAM-1)
Affinity DataIC50: 980nMAssay Description:Inhibition of KDM5C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223317(KDOAM-1)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM191598(KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM34737(2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant KDM5B catalytic core (1 to 729 residues) (unknown origin) expressed in baculovirus infected insect cells by FDH coupled ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM34571(6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50498665(CHEMBL1982368)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM26119(2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of KDM4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481821(CHEMBL5277129)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of KDM5B in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5C(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50498665(CHEMBL1982368)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of KDM5C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM14672(cid_311 | CITRIC ACID | 2-hydroxypropane-1,2,3-tri...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM26121(Succinic acid, 6 | butanedioic acid | Succinate | ...)
Affinity DataIC50: 1.40E+6nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | L-2-Hydroxygluta...)
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50: 3.60E+6nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed