Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018759
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612120BDBM50612120(CHEMBL5275705)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50468271BDBM50468271(CHEMBL4290134)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505333BDBM50505333(CHEMBL4437173)
Affinity DataIC50: 7nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019166BDBM50019166(CHEMBL336718)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505333BDBM50505333(CHEMBL4437173)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human recombinant TNKS2 expressed in Escherichia coli assessed as inhibition at 20 uM measured after 48 hrs by fluorescence based analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511566BDBM50511566(CHEMBL4448872)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant TNKS2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188337BDBM50188337(CHEMBL2058057)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612121BDBM50612121(CHEMBL5277753)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511566BDBM50511566(CHEMBL4448872)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TNKS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612117BDBM50612117(CHEMBL5270676)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612118BDBM50612118(CHEMBL3431396)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Srinath College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612119BDBM50612119(CHEMBL5267866)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant full length TNKS1 (1030 to 1317 residues) expressed in Escherichia coli assessed as inhibition by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)