Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50011883
TargetGrowth hormone secretagogue receptor type 1(Rat)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50552132(Spiropiperidine)
Affinity DataEC50:  50nMAssay Description:Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Rat)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50552133(CHEMBL4765101)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Rat)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50083974(CP-424391-18 | 2-Amino-N-[(R)-2-((R)-3a-benzyl-2-m...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422151(CHEMBL88239)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin A receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataIC50: 100nMAssay Description:Inhibition of MDM2 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422148(CHEMBL317181)
Affinity DataIC50: 155nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin A receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422152(CHEMBL432015)
Affinity DataIC50: 282nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin B receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422148(CHEMBL317181)
Affinity DataIC50: 832nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin B receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422152(CHEMBL432015)
Affinity DataIC50: 1.32E+3nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin A receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50422151(CHEMBL88239)
Affinity DataIC50: 8.32E+3nMAssay Description:Displacement of [125I]Bolton-Hunter CCK8 from human Cholecystokinin B receptor expressed in CHO-K1 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  0.880nMAssay Description:Inhibition of FAM tagged p53-based peptide binding to recombinant human His-tagged MDM2 protein (residues 1 to 118 residues) incubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM21173(DPCPX | CHEMBL183 | 8-cyclopentyl-1,3-dipropyl-2,3...)
Affinity DataKi:  6.40nMAssay Description:Displacement of N6-[3H]cyclohexyladenosine from adenosine receptor A1 in guinea pig forebrain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50004593(CHEMBL106548 | 1,3-Dipropyl-8-(2,2,5,5-tetramethyl...)
Affinity DataKi:  22nMAssay Description:Displacement of N6-[3H]cyclohexyladenosine from adenosine receptor A1 in guinea pig forebrain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed