Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50018336
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422776(CHEMBL5078139)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PFKFB3 (unknown origin) incubated for 90 mins by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422778(CHEMBL5273875)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PFKFB3 (unknown origin) incubated for 90 mins by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422777(CHEMBL5076616)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PFKFB3 (unknown origin) incubated for 90 mins by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 30nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422779(CHEMBL5272308)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant His-tagged PFKFB3 expressed in Escherichia coli using Fructose-6-phosphate incubated for 2 hrs in presence of ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422780(CHEMBL5286061)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant His-tagged PFKFB3 expressed in Escherichia coli using Fructose-6-phosphate incubated for 2 hrs in presence of ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200914(US9233946, 13)
Affinity DataIC50: 80nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM267057(2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PFKFB3 in human PANC-1 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM267057(2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PFKFB3 in human MIA PaCa-2 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM267057(2-Hydroxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PFKFB3 in human NUGC-3 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200934(US9233946, 33)
Affinity DataIC50: 130nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422770(Pfk-158 | PFK-158)
Affinity DataIC50: 137nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422774(CHEMBL5272966)
Affinity DataIC50: 150nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200939(US9233946, 38)
Affinity DataIC50: 180nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50095995(7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethy...)
Affinity DataIC50: 183nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443265(CHEMBL5285350)
Affinity DataIC50: 190nMAssay Description:Inhibition of PFKFB3 (unknown origin) pre-incubated for 15 mins measured after 20 mins in presence of ATP by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422771(CHEMBL5281032)
Affinity DataIC50: 200nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50445946(CHEMBL3105836)
Affinity DataIC50: 207nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443268(CHEMBL5270052)
Affinity DataIC50: 251nMAssay Description:Inhibition of full-length human PFKFB3 (1 to 520 residues) incubated for 2 hrs in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422772(CHEMBL5289308)
Affinity DataIC50: 280nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200915(US9233946, 14)
Affinity DataIC50: 280nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422773(CHEMBL5270896)
Affinity DataIC50: 290nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443269(CHEMBL5287238)
Affinity DataIC50: 398nMAssay Description:Inhibition of full-length human PFKFB3 (1 to 520 residues) incubated for 2 hrs in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443266(CHEMBL5276596)
Affinity DataIC50: 398nMAssay Description:Inhibition of full-length human PFKFB3 (1 to 520 residues) incubated for 2 hrs in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50508526(CHEMBL4542245)
Affinity DataIC50: 480nMAssay Description:Inhibition of PFKFB3 in human HCT-116 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422781(CHEMBL5271413)
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant His-tagged PFKFB3 expressed in Escherichia coli using Fructose-6-phosphate incubated for 2 hrs in presence of ATP by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443270(CHEMBL3729661)
Affinity DataIC50: 500nMAssay Description:Inhibition of PFKFB3 (unknown origin) by UV-vis spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200909(US9233946, 8)
Affinity DataIC50: 610nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50443267(CHEMBL5282621)
Affinity DataIC50: 631nMAssay Description:Inhibition of full-length human PFKFB3 (1 to 520 residues) incubated for 2 hrs in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50209568(7,8,4'-trihydroxyisoflavone | 7,8-dihydroxy-3-(4-h...)
Affinity DataIC50: 670nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422770(Pfk-158 | PFK-158)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PFKFB3 in human Jurkat cells incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PFKFB3 in human PANC-1 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422779(CHEMBL5272308)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of PFKFB3 in human HCT-116 cells assessed as inhibition of glucose induced lactate production by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM200981(US9233946, 80)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422780(CHEMBL5286061)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of PFKFB3 in human HCT-116 cells assessed as inhibition of glucose induced lactate production by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50445948(CHEMBL3105848)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50422775(CHEMBL4751366)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50095995(7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethy...)
Affinity DataKi:  94nMAssay Description:Binding affinity to PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50209568(7,8,4'-trihydroxyisoflavone | 7,8-dihydroxy-3-(4-h...)
Affinity DataKi:  240nMAssay Description:Binding affinity to PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity to PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed