Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50011042
TargetInterleukin-1 receptor antagonist protein(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Arg-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM85550(cid_123814 | CHEMBL261120 | CAS_12676-15-2 | Ang I...)
Affinity DataIC50: 251nMAssay Description:Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of ERAP2 (unknown origin) using Arg-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM85550(cid_123814 | CHEMBL261120 | CAS_12676-15-2 | Ang I...)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of ERAP2 (unknown origin) using Arg-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM85550(cid_123814 | CHEMBL261120 | CAS_12676-15-2 | Ang I...)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of ERAP1 (unknown origin) using Leu-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed